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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Fei Lin

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Open access Aug 2026

TRIM59 Drives Bladder Cancer Progression Through E3 Ligase‐Dependent K48‐Linked Degradation of PTRF

ABSTRACT Tripartite motif‐containing 59 (TRIM59) is an E3 ubiquitin ligase implicated in multiple malignancies, but its role in bladder cancer (BLCA) remains incompletely understood. In this study, we identified TRIM59 as a clinically relevant oncogenic driver in BLCA through integrated transcriptomic, clinical, and fu...

Junlin Gan, Xuesong Bai, Aijie Zhang et al. · 0 citations
Jul 2026

Ambient PM2.5 exposure is associated with clear cell renal cell carcinoma aggressiveness and promotes tumor progression through ROS-mediated AKT/HIF-2α signaling.

Ambient fine particulate matter (PM2.5) is an established environmental health hazard, but its role in clear cell renal cell carcinoma (ccRCC) progression remains incompletely understood. This study integrated epidemiological analysis, mechanistic experiments, transcriptomic profiling, and clinical tissue validation to...

Xiao-Hui Wu, Wen-Cai Zheng, Wen-Tao Xu et al. · 0 citations

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