Spatial Analysis Dissects the Microenvironmental Architecture of Local Recurrence after Breast-Conserving Surgery.
Ipsilateral breast tumor recurrence (IBTR) is a critical prognostic determinant in breast cancer patients undergoing breast-conserving surgery (BCS). The spatial arrangement of immune, stromal, and malignant cells can influence local recurrence progression and treatment efficacy in IBTR tumors. Here, we performed singl...