Author

Fei Wang

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Open access Aug 2026

The KAT8-CDK1 K33 acetylation axis drives doxorubicin resistance by suppressing ferroptosis and apoptosis in breast cancer

KAT8-dependent CDK1 K33 acetylation is established as a key epigenetic mechanism sustaining anthracycline resistance and targeting the KAT8-CDK1 axis may provide a therapeutic strategy to overcome refractory breast cancer.

Qing-Zhi Zhao, Qi-Xian Zou, Jin-Meng Chu et al. · Cell Death and Disease · 0 citations