Author

Fei Yang

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Open access Nov 2026

Integrative analysis reveals shared biomarkers and pathways in osteoporosis and rheumatoid arthritis using machine learning and single-cell sequencing

Background Osteoporosis (OP) and Rheumatoid Arthritis (RA) are prevalent chronic diseases characterized by bone loss and immune dysregulation. Evidence suggests that patients with RA are at increased risk of developing OP; however, the shared molecular mechanisms linking these conditions remain incompletely understood....

Jing-Shu Zhao, Yi-Xuan Chen, Fei Yang et al. · PLoS ONE · 0 citations

Sep 2026

SOX9 attenuates osteoarthritis bNy regulating autophagy via the PI3K/Akt/mTOR pathway.

The pathogenesis of osteoarthritis (OA) has remained unclear, posing a clinical challenge. Although SRY-box transcription factor 9 (SOX9) has been reported to inhibit OA progression, the specific mechanisms through which it regulates inflammation in OA, especially with respect to chondrocyte autophagy, remain poorly un...

Jun Qin, Zai-Nen Qin, Ke Ma et al. · International Journal of Bio... · 0 citations