Open access
Sep 2026
Integrative single-cell and bulk transcriptomics uncovers a lipid metabolism-related lncRNA signature alongside the ELFN1-AS1/LYPLA1 axis driving osteosarcoma progression
The oncogenic ELFN1-AS1/LYPLA1 regulatory cascade is characterized as a potential biomarker and therapeutic target for precision management of osteosarcoma and establishes an LMRL-based for osteosarcoma prognostic stratification that reflects immune, genomic and therapeutic heterogeneity.
Xian-Fu Wei, Zhi-Peng Wang, Qiang Yang et al.
· Frontiers in Immunology · 0 citations