Feifei Guan

A deep learning and generative modeling pipeline for mining and engineering alkaline-stsable xylanases.

A transfer learning-based predictor for acidophilic and alkalophilic proteins, trained on a curated non-redundant dataset, and an integrated pipeline for mining and engineering alkalophilic and thermophilic enzymes, combining sequence-based prediction, generative modeling, and multi-parameter virtual screening are developed.