Feixiong Cheng

Quantum Sampling Architecture for Protein Structure Reconstruction on Utility-Scale Hardware

QSAD is presented, a quantum-classical framework that reformulates peptide structure prediction as amino-acid-level Hamiltonian sampling and replaces iterative optimization with non-iterative Hamiltonian evolution and establishes coarse-grained quantum sampling as a practical computational path for structure prediction in regimes where data-driven methods lack sufficient signal.