Open access
Sep 2026
Longitudinal transcriptomic profiling of paired early and metastatic EGFR-mutant lung adenocarcinomas reveals molecular programs associated with disease progression.
BACKGROUND The molecular mechanisms driving the progression of EGFR-mutated lung adenocarcinoma (LUAD) from localized to metastatic disease remain incompletely understood. We aimed to characterize transcriptomic alterations associated with disease progression by analyzing longitudinally paired tumor samples from patien...
Alejandro Pallares Robles, P. Christopoulos, M. Allgäuer et al.
· Lung Cancer · 0 citations