Fen Gao

Yttrium( III )‐Catalyzed Desymmetrization of 2‐Fluoro‐1,3‐indanediones via Allylation towards Chiral 3‐Hydroxyindanones Bearing Quaternary C–F Stereogenic Centers

3‐Hydroxyindanone represents one of the most valuable and privileged cyclic scaffolds in synthetic and medicinal chemistry, which widely exists in a variety of biologically active natural products and pharmaceutical lead molecules. Benefiting from its reactive hydroxyl and carbonyl functional groups, the 3‐hydroxyind...