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Open access Aug 2026

HABP4/VIM-Mediated Focal Adhesion Assembly Regulates Enteric Neural Crest Cell Migration via the FAK/SRC Pathway.

BACKGROUND The enteric nervous system (ENS) arises from enteric neural crest cells (ENCCs), and defects in this process can lead to Hirschsprung's disease (HSCR), a congenital disorder characterized by the absence of enteric neurons in the distal colon. Our previous work has identified HABP4 as a potential susceptibili...

Huifang Lin, Jun Xiao, Ziyi Zheng et al. · 0 citations
Aug 2026

ALK regulates macrophage polarization via the USP7/SOX9/MFAP2-mediated glycolytic pathway to promote neuroblastoma progression.

Findings identify the ALK/USP7/SOX9/MFAP2 cascade as a critical regulator of metabolic reprogramming and immune evasion in NB, and suggest that targeting this axis may represent a promising therapeutic strategy for high-risk NB.

C. Lai, Kun-Ting Xu, Renfu Li et al. · 0 citations

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