Novel histone deacetylase 6 gene variant is associated with fetal hydrocephalus and lateral ventriculomegaly.
OBJECTIVES Congenital hydrocephalus (CH) is a neurological disease that significantly impacts fetal nervous system development and subsequent quality of life. CH pathogenesis may be linked to genetic factors such as defects in the histone deacetylase 6 (HDAC6) gene. However, only one CH family has been reported to date...