Author

Feng-Chuan Cao

2 papers indexed here

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Aug 2026

Anti-breast cancer effects of the Xingxiao Pill are associated with inhibition of the ErbB3/PI3K/AKT/mTOR pathway, modulation of amino acid metabolism, and promotion of apoptosis.

ETHNOPHARMACOLOGICAL RELEVANCE The Xingxiao Pill (XXP), a representative traditional Chinese medicine (TCM) formula used to promote blood circulation and remove blood stasis in tumor therapy, has shown promising clinical potential. According to the book Famous Traditional Chinese Medicine Formulas and Case Studies for...

Jingyue Zhang, Jian-Bang Cheng, Feng-Chuan Cao et al. · Journal of Ethnopharmacology · 0 citations

Open access Sep 2026

CAFs-mediated histone lactylation reprograms cholesterol metabolism in colorectal cancer to drive CD8+ T cell immunosuppression.

The central role of the CAF-CRC cell-CD8+ T cell regulatory axis is systematically elucidates: CAF-derived lactate modulates cholesterol metabolism in CRC cells via histone lactylation, thereby triggering mitochondrial dysfunction and driving the cellular senescence process.

Hua-Chi Li, Jun-Jie Hu, Lei Huang et al. · Journal of Pathology · 0 citations