On-chip engineering of EDC-crosslinked antimicrobial peptide hydrogels for enhanced eradication of MRSA infections
This study developed a controlled slow-release antimicrobial peptide (AMP) hydrogel to address the hemolytic side effects that limit AMP clinical application. Innovatively employing microfluidic-assisted 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC) coupling, the antimicrobial peptide (HfAMP) was covalently conj...