Kaempferol Counteracts Obesity and Impairs Adipogenesis by Suppressing PI3K/AKT/GSK3β-Mediated Mitotic Clonal Expansion and Attenuating Adipose Tissue Fibrosis.
Kaempferol, a widely present dietary flavonoid in numerous fruits and vegetables, possesses antiobesity potential with unclearly defined mechanisms. This study investigated how kaempferol regulates adipogenesis in 3T3-L1 preadipocytes and exerts antiobesity effects in high-fat diet (HFD)-induced obese mice. Kaempferol...