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Author

Feng Lu

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Open access Jul 2026

Bioinformatics identification of candidate biomarkers associated with T cell proliferation in atherosclerosis via WGCNA and machine learning.

It is suggested that CLU and GUCY1B3 may serve as candidate biomarkers warranting further experimental investigation in AS associated with T cell proliferation, and a nomogram constructed from these biomarkers showed good performance in predicting AS risk.

Wen Xiong, Xiang Long, Feng Lu et al. · 0 citations
Jul 2026

PNPT1-induced mitochondrial dysfunction drives osteoclast activation via post-transcriptional Nrf2 suppression and lipid peroxidation signaling.

By inciting mitochondrial damage, provoking ROS buildup, and decoupling the protective autophagy-Nrf2/xCT axis, PNPT1 promotes osteoclastogenesis, thereby introducing a promising immunopharmacological target for restraining pathological bone resorption.

Cheng-Yan Liu, Xinlin Nie, Fangze Xing et al. · 0 citations

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