Sep 2026
IL-1β-driven SERPINE1 Upregulation is Associated with CAD-ICM-related Cardiomyocyte Remodeling.
INTRODUCTION Coronary artery disease (CAD) may progress to ischemic cardiomyopathy (ICM) and heart failure through maladaptive cardiomyocyte remodeling and myocardial fibrosis. This study aimed to identify key molecular mediators linking inflammatory and fibrotic signaling during this pathological transition. METHODS...
Ke-Xin Chen, Xing-Yu He, Xiang-Ming Ning et al.
· Current Drug Targets · 0 citations