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Author

Feng-Xian Ni

3 papers indexed here

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Review Aug 2026

Cuproptosis: The metabolic-immune axis in chronic obstructive pulmonary disease pathogenesis and therapeutics.

Chronic Obstructive Pulmonary Disease (COPD) remains a leading cause of global morbidity and mortality, characterized by progressive airflow limitation and chronic inflammation that current therapies fail to effectively modify. The recent discovery of cuproptosis-a copper-dependent, regulated cell death mechanism drive...

Feng-Xian Ni, Jie Hu, Pei-sheng Chen et al. · 0 citations
Review Open access Aug 2026

Oxidative stress-driven epigenetic reprogramming of immune cells in COPD: from epitranscriptomic and metabolic crosstalk to treatable traits

Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome characterized by persistent oxidative stress and maladaptive immune responses, rather than a single disease entity. Oxidative stress not only damages lung tissue but also reprograms immune cells through both classical epigenetic mechanisms (DNA me...

Chun-Feng Pan, Qiong Wan, Feng-Xian Ni et al. · 0 citations
Review Open access Aug 2026

Epitranscriptomics, immunometabolism, and NETosis: unlocking novel mechanisms of traditional Chinese medicine in COPD

The bidirectional metabolism-m6A crosstalk as a theoretical framework requiring experimental validation, and single-cell m6A sequencing, spatial metabolomics, and CRISPR screening as tools to accelerate precision TCM for COPD are outlined.

Hui-Hui Chen, Feng-Xian Ni, Dong-Hui Huang et al. · 0 citations

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