Feng-Xiang Wei

Clinical Performance Evaluation of Size-Selective Placental Cell-Free DNA Enrichment for Non-Invasive Prenatal Testing of Fetal Copy Number Variants.

OBJECTIVE To evaluate the performance of low-depth non-invasive prenatal testing (NIPT) using cell-free DNA enrichment for detecting fetal copy number variations (CNVs) and to assess its clinical utility. METHODS A retrospective analysis was conducted on 86,012 pregnant women who underwent NIPT with size-selective ce...

Comparative Screening Performance of Noninvasive Prenatal Testing in Assisted Reproduction and Spontaneous Pregnancies.

OBJECTIVE To compare noninvasive prenatal testing (NIPT) performance between pregnancies conceived with assisted reproductive technology (ART) and spontaneously conceived pregnancies, and explore NIPT application characteristics in the ART population. METHOD A single-center retrospective study enrolled 193,376 pregna...

Genome-wide association analyses of gestational phenotypes identify context-specific genetic effects