HSTXGB: a hyperparameter self-tuning XGBoost method integrating pre- and post-processing for gene regulatory network inference
A network structure refinement scheme, termed HSTXGB (a hyperparameter self-tuning XGBoost method integrating pre- and post-processing), to infer GRNs from time-course expression data by leveraging the nonlinear modeling capability of XGBoost while integrating prior knowledge and posterior statistics.