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Open access Sep 2026

CPT1A as a metabolic gatekeeper linking fatty acid oxidation, ferroptosis resistance, and breast cancer stemness

Breast cancer stem-like cells sustain residual disease, metastatic recurrence and resistance to systemic and local therapies. Their defining metabolic feature is not a fixed preference for glycolysis or oxidative phosphorylation, but the capacity to reallocate substrates while preserving energy and redox homeostasis. C...

Feng Zeng, Xing-Han Chen, Kai-Guo Long et al. · 0 citations

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