Open access
Aug 2026
Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix
ABSTRACT Chronic glucocorticoid (GC) exposure is the leading clinical cause of skeletal muscle atrophy, steroid myopathy, and secondary sarcopenia, triggering irreversible motor function decline, disease progression, and elevated all‐cause mortality. The underlying pathological mechanisms remain unclear, and no safe an...
Hongwei Shi, Xiaojing Hao, Yi Yan et al.
· Advancement of science · 0 citations