Author

Fenna M. Krienen

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Review Open access Sep 2026

GABAergic interneurons in local circuits of primate prefrontal cortex.

Cortical GABAergic interneurons exhibit remarkable diversity of morphological, electrophysiological and molecular features, which underlies their specialized roles in circuit functions. Molecular characteristics have proven to be a reasonable starting point in the past for classification, grouping them into parvalbumin...

S. Pommer, D. Lewis, F. Krienen et al. · Biological Psychiatry · 0 citations

Open access Aug 2026

PIANO: Probabilistic Inference Autoencoder Networks for multi-Omics enables robust generative modeling of gene expression and scales single-cell integration to 100 million cells

PIANO accurately integrates single-cell data across species and across single-cell and spatial transcriptomics modalities and models spatially-resolved gene expression during Alzheimer’s disease progression in human brains and integrates over 100 million cancer cells to model drug perturbations.

Ning Wang, Christopher Cardenas, Victor E. Nieto-Caballero et al. · bioRxiv · 0 citations