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Author

Fernando Chimal-Cázares

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Open access Aug 2026

TagR, a newly identified member of the MarR family of transcriptional regulators, represses the NRPS operon in Klebsiella oxytoca

ABSTRACT Toxigenic Klebsiella oxytoca strains produce the pyrrolobenzodiazepine enterotoxins tilimycin (TM) and tilivalline (TV), which contribute to the development of antibiotic-associated hemorrhagic colitis. The biosynthesis of these toxins depends on the nonribosomal peptide synthetase (NRPS) operon located within...

Cristopher Perez, M. A. López-Luis, Carlos J Jiménez-Sánchez et al. · 0 citations

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