BACKGROUND
Intranasal corticosteroids (INS) are first-line therapy for pediatric allergic rhinitis (AR), but their delayed onset may undermine early adherence. We evaluated a 5-day topical decongestant "bridge" added to INS in children with persistent AR.
METHODS
In this prospective, open-label, single-center randomi...
N. Yüksel, Özlem Sancaklı, Figen Çelebi Çelik et al.· International Journal of Ped...· 0 citations
Highlights What are the main findings? This tertiary-center cohort supports viewing pediatric DOCK8 deficiency as an actin cytoskeleton-related IEI with overlapping infectious, allergic, immune-dysregulatory, and systemic manifestations. Beyond eczema and recurrent infections, the cohort included cytopenias, autoimmuni...
Figen Çelebi Çelik, N. Yüksel, Ömer Akçal et al.· Children· 0 citations
Inborn errors of immunity (IEIs) are a heterogeneous group of genetic disorders in which timely diagnosis is essential for appropriate treatment and improved clinical outcomes. Although next-generation sequencing provides definitive molecular confirmation, it is often time-consuming, costly, and may not identify al...
Özgen Soyöz, Figen Çelebi Çelik, M. Kaya et al.· Frontiers in Immunology· 0 citations
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