Author

Filip Sente

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Open access Aug 2026

Evolution of human IL4I1 preference for aromatic amino acids from a broad-specificity L-amino acid oxidase ancestor.

The findings demonstrate that the functional divergence between human IL4I1 and venomous snake LAAOs is underpinned by evolutionary shifts in substrate specificity and catalytic efficiency.

Marta Massari, Jonatan Caroli, Marco Malatesta et al. · Proceedings of the National... · 0 citations