Optimized Gradient Waveforms for Tensor-Valued Diffusion MRI Under Time-Dependent Diffusion Using Double-Isotropic Matched Encoding (DIME).
PURPOSE Spherical and linear b-tensor encoding (STE and LTE) enables quantification of microscopic diffusion anisotropy and diffusional variance. However, such waveforms are often variably sensitive to time-dependent diffusion, causing rotational variance and spectral mismatch. We propose double-isotropic matched encod...