Reproduction is one of the most fundamental biological processes in the human body, yet the molecules governing it remain incompletely understood. Here, we have characterized the role of PKHD1L1 and its globally relatively common splice donor variant rs17368310 in female fertility. We demonstrate estrogen-responsive ex...
E. Kapiainen, M. Karjalainen, P. Petrov et al.· medRxiv· 0 citations
For most diseases, whether PRS improves prediction beyond clinical data remains unknown, as existing evidence is concentrated in a handful of conditions with established risk models. Using 900,000 participants from UK Biobank and FinnGen, we developed and validated models for predicting 150 diseases and all-cause morta...
D. Usoltsev, I. Molotkov, N. Kolosov et al.· medRxiv· 0 citations
A genome-wide association study across three large cohorts of dermatochalasis detected 18 genetic loci associated with dermatochalasis, characterized these loci in detail and demonstrated their relevance in skin biology and related processes.
K. Rajueni, F. Koskimaki, V. Salo et al.· medRxiv· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
