Frances D H Zorensky

NET1 mRNA localization to the midbody is required for Arp2/3-dependent initiation of mitotic abscission

The recruitment and activation of abscission machinery following mitosis is tightly spatiotemporally regulated, yet the mechanisms underlying this remain poorly understood. We find that RNA localization and local translation at the midbody governs when and where abscission-regulating proteins are expressed. The 3′ UTR...