In this real-world emulated multicentre clinical trial, bDMARDs showed comparable overall trajectories of short-term effectiveness and long-term treatment persistence in PsA and the identification of partially distinct response patterns may support a more individualised approach to bDMARD selection.
P. Ruscitti, F. Masedu, I. Pantano et al.· Annals of the Rheumatic Dise...· 0 citations
Risankizumab was associated with clinical benefit and acceptable treatment persistence, even if larger studies are needed, even if larger studies are needed.
Francesco Caso, E. Celletti, I. Pantano et al.· Expert Opinion on Biological...· 0 citations
Abstract Janus kinase (JAK) inhibition is an established therapeutic strategy in rheumatoid arthritis, but heterogeneous treatment responses, persistent safety concerns, and the need for more precise therapeutic positioning continue to stimulate the development of additional JAK-directed compounds. This structured narr...
Luisa Costa, Francesco Caso, F. Maione et al.· Drug Design, Development and...· 0 citations
ABSTRACT Introduction Still’s disease is a systemic inflammatory disorder characterized by a complex cytokine network involving interleukin (IL)-1, IL‑6, IL‑18 and interferon (IFN)-γ. Although IL‑1 and IL‑6 inhibitors represent the cornerstone of current targeted therapy, a subset of patients remains refractory or deve...
P. Ruscitti, F. Ursini, R. Giacomelli et al.· Expert Opinion on Pharmacoth...· 0 citations
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