Franck Sturtz

Oxidative stress in diabetic peripheral neuropathies: Key mechanisms and therapeutic targets

Oxidative stress plays a central and multifaceted role in the pathogenesis of diabetic peripheral neuropathies (DPN), one of the most common and disabling complications of diabetes mellitus. Chronic hyperglycemia initiates a cascade of interrelated metabolic disturbances including activation of the polyol, hexosamine,...