Review
Jul 2026
Restoring Cancer Genomes: Functional Mutation Correction as a Platform for Precision Oncology
Cancer genome sequencing has uncovered an extensive landscape of somatic mutations. However, determining which of these alterations are biologically consequential and therapeutically actionable remains a central challenge in oncology. CRISPR-based genome editing now enables precise correction of oncogenic mutations wit...
Pascal Wang, Shady Sayed, Frank Buchholz
· Human Gene Therapy · 0 citations