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Author

Frank Momburg

2 papers indexed here

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Open access Aug 2026

T-Cell Receptor Single-Chain Antibody IgG1-Fc Fusion Proteins as Bispecific Engagers for Natural Killer and T Cells

Highlights What are the main findings? Novel trifunctional NK cell engagers have been developed that combine the ADCC-eliciting function of IgG1 Fc parts and NK cell-targeting mini antibodies with the capacity of T cell receptors to specifically recognize intracellular peptide antigens presented by MHC molecules Antibo...

Annkathrin C. Teschner, Márcia Gonçalves, Marten Meyer et al. · 0 citations
Open access Aug 2026

T-cell engager bispecific antibodies enable T cells to eliminate Multiple Myeloma by targeting tumor CD38 in combination with PD-L1

Bispecific antibodies have gradually been applied in the treatment of multiple myeloma(MM). The combination of bispecific antibodies targeting CD3 and CD28 mimics the dual-signaling system (antigen signaling and co-stimulatory signaling) of natural T cell activation, thereby significantly enhancing the anti-tumor res...

Chaofan Wang, Wanting Wang, Mo-Ran Wang et al. · 0 citations

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