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Review Sep 2026

Biomaterial-based mitochondria-targeted nanomedicine for remodeling the breast cancer tumor microenvironment and overcoming therapy resistance.

Breast cancer treatment remains limited by therapeutic resistance, recurrence, and incomplete responses to immunotherapy, largely because tumor cells continuously adapt to the dynamic tumor microenvironment (TME). Mitochondria are central regulators of energy metabolism, redox balance, cell death, inflammatory signalin...

Yao Gu, Peng Qu, Xue Li et al. · 0 citations
Open access Aug 2026

Routine metabolic and nutrition-related composite indices for identifying adverse cardiovascular-kidney-metabolic phenotypes: a cross-sectional study

Background Cardiovascular-kidney-metabolic (CKM) syndrome provides an integrated framework for capturing the overlap of adiposity, metabolic dysfunction, kidney impairment, and cardiovascular risk. Whether low-cost composite biomarkers derived entirely from routine health examinations and brief questionnaires can ident...

Jing Lin, Guang-Re Xu, Fu-Li Chen et al. · 0 citations

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