LC-MS-Guided Identification of Bioactive Constituents in Qingfei Jiedu Huatan Formula Reveals Ginsenoside Rb1 as an Endothelial Barrier-Protective Compound Targeting PAI-1 in Pneumonia.
INTRODUCTION Qingfei Jiedu Huatan Formula (QJHF) is a traditional Chinese medicine formula developed for severe pneumonia with the syndrome of "phlegm heat obstructing the lung." PURPOSE This study aimed to investigate the protective effects and underlying mechanisms of QJHF on pulmonary vascular endothelial barrier...