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Review Open access Oct 2026

Risk factors of major bleeding associated with direct oral anticoagulant treatment in patients with venous thromboembolism: a systematic review and meta-analysis

Background Direct oral anticoagulants (DOACs) are commonly prescribed for venous thromboembolism (VTE), but major bleeding (MB) remains an important complication of treatment. Despite their widespread use, systematic evaluations of prognostic factors associated with major bleeding during DOAC treatment remain scarce. T...

Hai-Rong Zhan, Fu-Xin Ma, Jin-Tuo Zhou et al. · 0 citations

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