110. Glutamatergic changes in the medial prefrontal cortex associated with psychosis history in bipolar disorder and their relationship to executive function
Elevated mPFC Glu and Glx in BD-P suggest that localized glutamatergic hyperactivity may underlie psychotic experience of BD, and the negative association between mPFC E/I ratio and cognitive flexibility observed only in BD-NP indicates that glutamatergic regulation of executive function differs by psychosis history.