Fujin Shi

Proximal Proteomics Reveals Potential Regulators of Programmed Death-Ligand 1 in Human Cancer

Programmed death-ligand 1 (PD-L1) is a key mediator of tumor immune evasion, but the protein networks governing its post-translational regulation remain incompletely understood. Here, we used PhastID-based proximity labeling to map the PD-L1 proximal proteome and integrated these data with pan-cancer proteomics and imm...