Aug 2026
Rational design of thiazolidine-2,4-dione-integrated combretastatin A-4 analogues as potent and selective tubulin-targeting agents for triple-negative breast cancer.
The present study identifies compounds 2 and 3 as promising lead candidate that combines potent and selective antiproliferative activity, strong tubulin polymerization inhibition, and favorable binding characteristics compared with paclitaxel.
F. S. Tokalı, Şeyma Ateşoğlu, Pelin Tokalı et al.
· European journal of medicina... · 1 citation