Review
Open access
Aug 2026
RNA splicing in health and disease
This review describes how spliceosome assembly, splicing regulatory elements, splicing factors, epigenetic modifications, and post-transcriptional processes determine splice-site selection and suggests that safe clinical translation will require greater selectivity, reduced off-target toxicity, and preservation of esse...
Huining Huang, Yao Yu, Qian Zhou et al.
· Molecular Biomedicine · 0 citations