Pancreatic ductal adenocarcinoma (PDAC) remains a leading cause of cancer-related mortality due to late-stage diagnosis and limited therapeutic targets. Most genome-wide association studies (GWAS) have focused on European populations, leaving the genetic landscape of PDAC in Asian populations under-characterized. Thi...
Yuan-Sheng Hsu, Tahira Akhtar, Huang-Wei Lo et al.· Cancer Research· 0 citations
BACKGROUND
Hepatic steatosis is a highly prevalent metabolic condition and a major contributor to chronic liver disease, particularly in Asian populations. This study was conducted to identify genetic variants associated with the severity of ultrasound-defined hepatic steatosis in a Taiwanese Han population and evaluat...
Background Blood lipids are heritable risk factors for cardiovascular disease (CVD), a leading cause of mortality worldwide. However, the genetic architecture of lipid traits and the performance of polygenic risk scores (PRSs) remain underexplored in East Asian (EAS) populations, including Taiwanese Han individuals. Me...
Yu-Chia Chen, Ting-Yuan Liu, Chi-Chou Liao et al.· Frontiers in Bioinformatics· 0 citations
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