Prophage Activation Triggers Extracellular Synthesis of DNA in Bacterial Biofilms via Rolling Circle Replication.
Extracellular DNA (eDNA) plays crucial roles in biofilm formation and function, yet the role of bacteriophages, which can exist in a dormant state as prophages, in controlling eDNA synthesis, structure, and activity remains obscure. Here, we demonstrate that prophages harbored by environmental bacteria can be exploited...