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G. A. Sadique

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Open access Aug 2026

Hypoxia-induced stromal and immune remodeling in gastric carcinoma: correlation of Hypoxia-inducible factor 1-alpha (HIF-1 alpha) expression with cancer-associated fibroblast (CAF) subtypes and Programmed death-ligand 1 (PD-L1) expression

High HIF 1 alpha expression and inflammatory CAF predominance are strongly associated with aggressive clinicopathological features and increased PD L1 expression, supporting the existence of a coordinated hypoxia stroma immune axis in gastric carcinoma progression.

G. A. Sadique, M. S. Mamun, S. Biswas et al. · 0 citations

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