SHBG as a breast cancer risk biomarker in premenopausal women? Results from an individual patient's pooled analysis and a meta-analysis.
BACKGROUND Low levels of sex hormone-binding globulin (SHBG) have been associated with increased breast cancer (BC) risk, particularly in postmenopausal women. Whether this association extends to premenopausal women remains uncertain. We therefore performed an individual-patient pooled analysis and a meta-analysis to e...