FROM EXPOSURE INDICES TO CELLULAR DAMAGE: A REVIEW ON INTEGRATED FRAMEWORK FOR GENOTOXICITY-INFORMED HEAVY METAL RISK ASSESSMENT
The heavy metal contamination of water, food, and soil is a widely recognized global problem. Yet the strategies commonly used to evaluate the impact of heavy metal contamination on human health typically do not account for the metabolic pathways of metals in living cells. Exposure metrics like Estimated Daily Intake,...