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Open access Aug 2026

A two-year single-site longitudinal assessment of brain and retinal atrophy in ocrelizumab-treated relapsing–remitting multiple sclerosis

Ocrelizumab is an effective treatment for relapsing–remitting multiple sclerosis (RRMS), but its impact on brain and retinal atrophy requires further investigation. To assess the effects of ocrelizumab on brain and retinal atrophy over two years and explore the relationship between imaging biomarkers, early inflammat...

M. Cellerino, C. Lapucci, S. Magon et al. · 0 citations
Nov 2025

DTI‐ALPS Primarily Reflects White Matter Diffusion Dispersion and Microstructural Heterogeneity in Neurodegeneration: Insights From Multi‐Modal MRI

Factor analysis indicated that DTI-ALPS clustered with MA and ODI rather than forming a distinct factor, suggesting that DTI-ALPS primarily reflects WM diffusion dispersion and heterogeneity rather than glymphatic flow in the context of neurodegeneration.

L. Sacchi, Giovanni Farruggio, Giorgio Bocca et al. · 1 citation

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