Author

G. Boons

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Open access Sep 2026

Substitutions affecting the HA–NA–receptor balance preceded the emergence of the pandemic 2009 H1N1 virus

Significance Influenza A pandemics greatly affect the human population every few decades when a novel animal virus breaches the species barrier. The H1N1 pandemic of 2009 (H1N1pdm09) is the first pandemic in the genomics era, which allows us to identify and study in detail mutations in prepandemic swine viruses associa...

K. Marougka, R. Leiva-Rebollo, Freeke Hofma et al. · Proceedings of the National... · 0 citations

Open access Jul 2026

Loss of hemagglutination ability by H3N2 influenza A virus, subclade K

How substitutions in or around the HA receptor-binding site affect binding to glycans at the molecular level is explored and previously established glyco-remodeled erythrocytes are efficiently bound by these subclade K H3N2 viruses and could support influenza surveillance and vaccine development.

Ruo-Nan Liang, P. Lexmond, Oliver C. Grant et al. · bioRxiv · 0 citations

Open access Aug 2026

Enhanced Pathogenicity and Contact Transmissibility of Human-origin Avian Influenza H5N1 Clade 2.3.4.4b Genotype B3.13 Compared to D1.1 in Ferrets

Using the ferret model of influenza infection and transmission, it is demonstrated that the currently circulating B3.3.13 is already well adapted for mammalian infection and transmission whereas D1.1 rapidly acquires mammalian-adaptive mutations after a single infection and/or transmission event, highlighting its evolu...

Ahmed M. Elsayed, Ramya S. Barre, Mahmoud Bayoumi et al. · bioRxiv · 0 citations