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G. Caruana

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Open access Oct 2026

Distinct profiles of white matter diffusivity in obesity and bipolar disorders: An ENIGMA bipolar disorders study in 2166 individuals

Abstract Background Bipolar disorders (BD) are associated with a wide range of brain white matter abnormalities, but results vary across studies. This heterogeneity likely relates to effects of additional clinical/diagnostic variables, including medications and obesity, on white matter in BD. In this mega-analysis, we...

Lorielle M. F. Dietze, Sean R. McWhinney, P. Favre et al. · 0 citations
Open access Aug 2026

Lifespan brain structural variation reveals shared organization across mental health conditions

Large-scale evidence is provided that structural deviations across NDPCs are systematically constrained by the brain's intrinsic architecture, providing a framework for reconciling individual variability with transdiagnostic similarities and motivates an integrative, systems-level understanding of mental health.

M. Hettwer, A. Saberi, G. Shafiei et al. · 0 citations

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