Review
Open access
Sep 2026
A bittersweet symphony: soluble mediator networks orchestrate melanoma plasticity and therapeutic adaptation
Melanoma progression and therapeutic resistance are increasingly recognized as emergent properties of the dynamic interactions between tumor cells and their surrounding tumor microenvironment (TME). A central feature of this adaptability is melanoma cell plasticity, through which tumor cells reversibly transition betwe...
Carmine Lauretta, Carmela Sorrentino, Emilia Sabbatino et al.
· Frontiers in Cell and Develo... · 0 citations