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Open access Aug 2026

The dystonia-associated Torsin1A sustains CLCC1 function in membrane fusion of the nuclear envelope for NPC biogenesis.

DYT1 dystonia is an incurable movement disorder caused by a loss-of-function mutation in Torsin1A, an endoplasmic reticulum (ER)-resident AAA+ ATPase. Here, we use Drosophila and human cells to shed light on Torsins' mode of action. Fly germ cells lacking dTorsin arrest in development with defects in nuclear pore compl...

D. Maslennikova, Harry J. M. Baird, Xinyue Ding et al. · 2 citations · ⚡1
Open access Jul 2026

Spatiotemporal control of cortical centrin patterning by regionalized Sfi1 family scaffolding proteins in Stentor coeruleus.

Patterning is fundamental to the development and maintenance of organisms, ensuring functional and structural organization. While patterning is well studied at the level of multicellular organisms, single cells also form spatial patterns. Stentor coeruleus is a ciliate that has been a classical system for studying patt...

Connie Yan, N. Steube, G. Dey et al. · 0 citations

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