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Open access Sep 2026

653. Effects of 10Hz transcranial focused ultrasound stimulation at the posterior cingulate cortex on cerebral glucose metabolism – a pilot fPET study

Abstract Background Transcranial focused ultrasound stimulation (TUS) is emerging as a promising method for non-invasive and safe modulation of neuronal activity throughout the human brain [1]. Although several centers worldwide have started to investigate TUS in patient collectives, dosing of sonication parameters rem...

G. Godbersen, M. Lückel, C. Milz et al. · 0 citations
Open access Sep 2025

Subacute effects of ketamine on neural correlates of reward processing

Objectives Ketamine’s prohedonic properties have been linked to enhanced reward-related brain activation during the early post-infusion phase. Its effects during the subacute period (∼2-24 h post-infusion), when psychotomimetic symptoms fade and neuroplastic adaptations emerge, are less well characterised. This study a...

E. Briem, P. Stöhrmann, G. Dörl et al. · 0 citations
Open access Sep 2026

572. Effects of 10Hz transcranial focused ultrasound stimulation of the posterior cingulate cortex on working memory performance – initial findings

Abstract Background Working memory impairments are common across various neuropsychiatric disorders (1). The posterior cingulate cortex (PCC) plays a central role in working memory function (2, 3). Low intensity transcranial focused ultrasound stimulation (TUS) offers a method to non-invasively modulate neuronal activi...

A. Harouak, C. Milz, P. Falb et al. · 0 citations
Open access Sep 2026

557. ECT-induced effects on brain structure, brain connectivity and cerebrospinal-fluid-based markers – a preliminary analysis

Abstract Background Electroconvulsive therapy (ECT) is among the most effective treatments for severe and treatment-resistant depression. Despite more than 90 years of clinical use, its underlying neurobiological mechanisms remain incompletely understood. One prominent hypothesis suggests that ECT induces neuroplastic...

P. Baldinger-Melich, S. Riessland, B. Spurny-Dworak et al. · 0 citations

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